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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease von willebrand disease
Comorbidity C0003507|aortic stenosis
Sentences 3
PubMedID- 20835786 Similar to acquired von willebrand's disease seen in patients with aortic stenosis, the shear stress of the cf-lvad may cause proteolysis of the hmw multimers of vwf.
PubMedID- 26269004 Unexpectedly high prevalence of acquired von willebrand syndrome in patients with severe aortic stenosis as evaluated with a novel large multimer index.
PubMedID- 21561895 Increased thrombin generation and platelet activation are associated with deficiency in high molecular weight multimers of von willebrand factor in patients with moderate-to-severe aortic stenosis.

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